International manufacturing networks have the potentialto deliver a wide range of capabilities. However, sound structureand a systematic management approach are crucial to realize thefull potential. In this article, we illustrate the applicability, strengthsand weaknesses of various tools and methods to analyze and optim-ize international manufacturing networks. Based on a case studyof a German specialty chemicals manufacturer with 19 sites world-wide, we outline procedure and identify critical success criteria foran analysis and implementation phase. The results of the researchserve as an orientation for managers with similar challenges and as a foundation forfurther research.