Gender and Graft-versus-Host Disease after Hematopoietic Stem Cell Transplantation
Journal
Biology of blood and marrow transplantation : BBMT
ISSN
1083-8791
ISSN-Digital
1523-6536
Type
journal article
Date Issued
2016-06
Author(s)
Gratwohl, Alois
;
Ruiz de Elvira, Carmen
;
Gratwοhl, Μichael
;
Greinix, Hildegard
;
Duarte, Rafael
Abstract
Highlights
•One third of HLA-identical sibling donor transplant recipients never ever develop any graft-versus-host disease
•This rate of no graft-versus-host disease is significantly higher with male donors in female recipients
•Factors associated with no graft-versus-host disease should become a target of precision medicine
•Prediction of no graft-versus-host disease could become a decision-guiding tool for early transplantations
•Such an approach could spare immunosuppression, improve survival, and reduce costs
•One third of HLA-identical sibling donor transplant recipients never ever develop any graft-versus-host disease
•This rate of no graft-versus-host disease is significantly higher with male donors in female recipients
•Factors associated with no graft-versus-host disease should become a target of precision medicine
•Prediction of no graft-versus-host disease could become a decision-guiding tool for early transplantations
•Such an approach could spare immunosuppression, improve survival, and reduce costs
Language
English
HSG Classification
contribution to scientific community
Refereed
Yes
Publisher
Elsevier Health Sciences
Volume
22
Number
6
Start page
1145
End page
1146
Subject(s)
Eprints ID
251390